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In this update, Professor Franken will explain how LC-MS can be used to investigate the various quality attributes of biopharmaceuticals.

Biopharmaceuticals are drugs that are produced with the help of biotechnology. In contrast to conventional small molecule drugs, which are chemically synthesized, biopharmaceuticals are usually derived from living organisms such as bacteria, yeast or mammalian cells. The structural complexity of protein-based biopharmaceuticals, such as antibodies, requires the use of a wide range of state-of-the-art analytical techniques.
LC-MS in particular is of crucial importance for biopharmaceuticals as it enables detailed analysis of complex molecules. It identifies and quantifies biomolecules and ensures product consistency and safety. Its precision supports quality control and regulatory compliance, making it essential for drug development.